Tricyclic Antidepressant Side Effects: A Quick Guide for Parents

Tricyclic antidepressants (TCAs) are older mood‑changing medicines that sometimes get prescribed for kids with depression, anxiety, or chronic pain. They work by changing how the brain handles certain chemicals, but they also affect many other parts of the body. That’s why side effects show up in places like the mouth, stomach, heart, and even the skin.

Common, Usually Mild Side Effects

Most kids notice a few harmless changes at first. Dry mouth is a classic TCA sign – your child may ask for water more often or complain of a sore throat. Constipation and a slower stomach can also happen, so adding fiber and fluids helps. Some children feel sleepy or a bit dizzy after the first few doses; this usually fades after a week or two.

Other mild issues include blurred vision, slight ringing in the ears, and a small uptick in appetite that might lead to weight gain. These symptoms are uncomfortable but not dangerous. If they bother your child, talk to the doctor about adjusting the dose or timing of the medication.

Serious Warning Signs You Can’t Ignore

TCAs can affect the heart’s rhythm, especially in kids with underlying heart problems. Watch for a fast or irregular heartbeat, chest pain, or fainting spells. Any of these deserve an immediate call to your pediatrician or a trip to urgent care.

Low blood pressure can make a child feel light‑headed or cause them to fall suddenly. Seizures are rare but possible, especially if the dose is too high or the child skips meals. Also, TCAs can increase the risk of suicidal thoughts in teens, so keep a close eye on mood changes, new irritability, or talk of self‑harm.

If you see any of these serious signs, seek medical help right away. Even if they seem mild at first, a doctor can run an ECG, check blood pressure, or adjust the treatment plan to keep your child safe.

Regular follow‑ups are key. The doctor will likely order blood tests to see how the liver is handling the medicine and may check the heart with an ECG. These visits help catch problems before they get big.

For everyday management, keep a simple side‑effect diary. Write down the date, what the child felt, and any actions you took (like giving water or adjusting meals). This log makes it easy for the doctor to see patterns and decide if the dose needs tweaking.

Remember, you’re not alone in this. Many parents feel nervous about TCAs, but with clear communication, careful monitoring, and quick action on serious symptoms, you can help your child get the benefits of the medication while minimizing risks.